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Onchodilators”.Other criteria that have been viewed as to be relevant by much more than of your pulmonologists and proposed as minor criteria were “personal history of allergy or sensitivity to 1 or far more allergens”, “elevated eosinophils in sputum or blood or high nitric oxide levels”, `diagnosis of asthma ahead of the age of “, “symptoms variability”, and “age (in favor of asthma)”.On top of that, the participants have been asked to pick the 3 most significant criteria to qualify a COPD patient as an ACOS patient.By far the most vital criteria, as chosen by with the pulmonologists, have been “degree of response to bronchodilators” and “degree of variability in airway obstruction”; “asthma diagnosis before years of age” was chosen by ; “personal or household history of atopy”submit your manuscript www.dovepress.comInternational Journal of COPD DovepressDovepressBelgian survey on aCOs diagnosisFigure Big criteria for diagnosing aCOs.Notes The bubble size and presented number and percentage (in gray) indicate the quantity and percentage of pulmonologists who deemed the criterion relevant for the diagnosis of aCOs.Overlap using the main reported criterion shows the amount of each combination (indicated in blue) of each answers provided by pulmonologists.Overlap in between the other criteria will not be shown.Abbreviations aCOs, asthma OPD overlap syndrome; FenO, fractional exhaled nitric oxide.Figure Options to diagnose a COPD patient as aCOs patient.Notes PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21466778 gray bars show the percentage of pulmonologists who viewed as the criterion as “relevant” (likert score).The two criteria viewed as relevant by most pulmonologists were retained as main criteria.Other criteria surpassing the cutoff mark for relevancy (vertical dashed line) had been regarded as as minor criteria.Black bullet shows imply likert score (with sD).Abbreviations aCOs, asthma OPD overlap syndrome; Ige, immunoglobulin e; FenO, fractional exhaled nitric oxide; CT, computed tomography; n, number of pulmonologists; sD, common deviation.International Journal of COPD submit your manuscript www.dovepress.comDovepressCataldo et alDovepressTable Criteria for aCOs diagnosis guidance in the Belgian surveyACOS in a COPD patient Important criteria higher degree of variability in airway obstruction more than time (PFTs) FeV variation ml high degree of response to bronchodilators (PFTs) ml and predicted above baseline Minor criteria Personal or loved ones history of atopy andor Ige sensitivity to one or a lot more airborne allergens elevated blood or sputum eosinophils or improved FenO Diagnosed with asthma prior to the age of symptom variability age (in favor of asthma) ACOS in an asthma patient Big criteria Persistence over time of airflow obstruction (persistence of FEVFVC ratio .or lower regular limit) exposure to A-196 Inhibitor noxious particles or gases, with packyears in case of smoking for (ex)smokers Minor criteria lack of response on acute bronchodilator test decreased lung diffusion capacity (on PFTs) small variability in airway obstruction (PFTs) age in favor of COPD (ie, years) Presence of emphysema on chest CT scanNote a diagnosis of aCOs is accepted in both COPD and asthma sufferers when the two significant criteria and at the least one minor criterion are met.Abbreviations aCOs, asthma OPD overlap syndrome; FeV, forced expiratory volume in second; FVC, forced important capacity; PFTs, pulmonary function tests; Ige, immunoglobulin e; FenO, fractional exhaled nitric oxide; CT, computed tomography.by ; and “elevated blood or sputum eos.

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