Plasmids from selected ten colonies were used as templates to amplify the CALR gene using cloning primers in PCR
Plasmids from every colony were isolated by employing QIAPrep Spin Miniprep columns (Qiagen, Valencia,...
Cell plating and treatment with compounds were as for the primary screen. Hit selection/confirmation criteria for quiescent cells were as described above
ASA-404 compounds ended up deemed as hits if relative ATP amounts in the respective...
Multiple regression analyses (including age, sex, smoking, diabetes, HbA1c and platelet count) were used to investigate determinants of platelet aggregation and platelet turnover
Multiple regression analyses (which includes age, intercourse, smoking, diabetic issues, HbA1c and platelet depend)...
Relative quantities of the identified proteins were represented by the quotient of the number of MS/MS normalized by total peptides identified in individual group and the summed PLGS scores of proteins
The Expression Analyses system with Automobile Normalization was employed for quantitation analysis. Relative quantities...
a downstream metabolite of HMG-CoA that was detected in the metabolomic analysis, was also not strongly affected at low glucose, but its increase induced by glucose was blunted by AICAR
1432908-05-8 farnesyl pyrophosphate (FPP), a downstream metabolite of HMG-CoA that was detected in the...
Additional modules were included in PyroTrop to assess the frequency of each amino acid at each position
Technique 4: the complete established of UDPS sequences was interpreted with our in-home software...
In the presence of oseltamivir, the relative fitness of either single mutant dominates over the wild-type. A simulated competition experiment between WT-I223 and MUT-I223V shows a larger total
In the presence of oseltamivir, the relative physical fitness of either single mutant dominates...
For quantification the biological replicates were separately analyzed and the protein relative abundance calculated for each sample
They are then scaled so they are all the same and the scaling issue...
This graph can also be used to generate treatment paths that start and end at the same genotype, making possible the development of a fixed treatment plan
This graph can also be used to produce treatment method paths that start off...
Cardiovascular parameters measured by magnetic resonance imaging at baseline (before) and one hour following the administration of Sildenafil or the placebo pill
Cardiovascular parameters calculated by magnetic resonance imaging at baseline (just before) and a single...